Patrick L. Purdon, PhD

Associate Professor of Anaesthesia at Harvard Medical School
Nathaniel M. Sims Endowed Chair in Anesthesia Innovation and Bioengineering at Massachusetts General Hospital

Patrick L. Purdon, Ph.D., is an Associate Professor of Anaesthesia at Harvard Medical School and the Nathaniel M. Sims Endowed Chair in Anesthesia Innovation and Bioengineering at Massachusetts General Hospital.  Dr. Purdon received his A.B. in Engineering Sciences from Harvard College in 1996, his M.S. in Electrical Engineering from MIT in 1998, and his Ph.D. in Biomedical Engineering from MIT in 2005.  Dr. Purdon’s research in neuroengineering encompasses the mechanisms of anesthesia, Alzheimer’s disease and brain health, anesthesia and the developing brain, neural signal processing, and the development of novel technologies for brain monitoring. He has published over 90 peer-reviewed publications, is an inventor on 16 pending patents, and is a Fellow of the American Institute for Medical and Biological Engineering.  Dr. Purdon has won numerous awards, including the prestigious National Institutes of Health Director’s New Innovator Award.

Postdoctoral Fellows

PEGAH KAHALI, MD

Pegah is interested in understanding the electrophysiological dynamics of local and global brain states, their neurometabolic determinants and underlying neurocircuitries
FENG LIU, PHD

Feng is interested in developing statistical and/or machine learning models to solve brain imaging problems using EEG/MEG recordings to better understand how our brain works.
LAURA A. SANTA CRUZ MERCADO, MD

The goal of Laura’s research is to investigate the underlying mechanisms of anesthetics action on the brain and the relationship between metabolic and immune brain state, neurophysiological circuits, and anesthetic drugs. In addition, Laura is interested in understanding the pathophysiology of cognitive disorders, as it relates to anesthesia and surgery, in different at-risk populations such as elderly, Alzheimer's, MS, cancer, septic, and IBD patients
EMILY P. STEPHEN, PHD

Emily uses statistical modeling and source localization techniques to study brain rhythms under anesthesia.
FANGYUN TIAN, PHD

Fangyun is interested in investigating the neurophysiological mechanisms of general anesthesia and consciousness using biomedical signal processing and statistical modeling approaches

Graduate Students

AMANDA BECK, MS
MIT PhD Candidate in Electrical Engineering and Computer Science

Amanda is interested in and pursuing signal processing methods to improve analysis of neural data, investigation of neurodegeneration, and design of neuromodulation systems. Amanda is also interested in a variety of medical research fields including precision medicine and AI for pathology.
MINGJIAN (ALEX) HE
HST MEMP PhD candidate

Alex is interested in understanding, diagnosing, and preventing Alzheimer’s disease with advanced signal processing and statistical modeling tools
GLADIA HOTAN
PhD candidate

Gladia is interested in EEG source localization, state-space modeling, functional connectivity
DAVID W ZHOU, MS
PhD candidate

David is interested in general anesthesia and disorders of consciousness.

Research Assistant and Lab Staff

TAYLOR DELP
Clinical Research Coordinator


Currently, Taylor has interest in all things medicine. He is infatuated with learning. He hopes to one day become a surgeon and provide acute medical care to those less fortunate in third world nations.
CHRISTOPHER COLVIN, MHSC
Senior Clinical Engineer


Christopher has been working in the areas of instructional design and healthcare human factors within the context of both research and quality improvement processes. He has been involved in the design of eLearning courses and educational content for promoting safe and effective practices for anesthesia management, medical device usage, and IV infusion delivery.
Sam Huang
Clinical Research Coordinator


Sam is interested in neurology, anesthesia, and all things related to the brain. He want sto help get a better understanding of the underlying mechanisms of neurodegenerative diseases such as Alzheimer's and to uncover potential treatments.
Jenny Tou
Clinical Research Coordinator


Jenny is interested in using the EEG as a window to understand the human brain, and as a tool to improve the care of neurological disorders.

Alumni

CHRIS GILL
Clinical Research Coordinator


Chris’s research interests are focused on investigating the relationship between visual perception, memory, and attention, understanding how these cognitive functions are affected by aging and neuropsychiatric disorders, and integrating this knowledge into diagnostic and therapeutic practices.
ANDREW MULLEN, BSC
MIT Masters Student – Department of Electrical Engineering and Computer Science

Andrew's research interests include clinical electrophysiology, systems neuroscience, and neuroscience methods development.
HUGO SOULAT
Research Assistant/ Data Analyst

Hugo’s research focuses on developing statistical tools to process neural data. His models are used to analyse EEG signals from subjects (and/or patients) under general anesthesia, and aim at characterizing the relationship between different neural rhythms. In doing so, he tries to provide a quicker, more efficient and more reliable estimate of the subject unconscious/unresponsiveness state.