The EEG should be transparent, highly accessible, physiologically-principled, and seamlessly compatible with current clinical practice.
This site includes a series of education modules based on the publications and lectures of Patrick L. Purdon, Ph.D. and Emery N. Brown, M.D., Ph.D. In these modules, anesthesiologists, CRNAs, and critical care physicians and nurses will learn how to read the electroencephalogram (EEG) to monitor brain states during general anesthesia and sedation.
Clinical EEG for Anesthesia
Using the EEG we can observe highly structured patterns related to different states of altered arousal. These patterns are related to the physiological actions of different anesthetic drugs on specific molecular targets, in specific neural circuits of the brain. With practice these EEG patterns can become easy to recognize and can be used to provide tailored, “personalized anesthesia care”.
This 2-part series will cover the essential information for understanding the EEG and what is represented in the EEG waveform and spectrogram. This series will also discuss the link between the neurophysiological mechanisms and EEG signatures of major anesthetic drugs: propofol, dexmedetomidine, ketamine, and inhaled anesthetics such as sevoflurane.
The Aging Brain
There are profound structural and functional changes in the brain that occur during typical aging. These changes make elderly patients (i.e., 60 years old and older) an extremely vulnerable patient group for anesthesia.
This 2-part series builds on the previous Clinical EEG for Anesthesia modules to discuss key insights on how anesthesia management differs between young and elderly patient groups and how we can provide better anesthesia care for elderly patients.
- Clinical Electroencephalography for Anesthesiologists Part 1: Background and Basic Signatures
- Electroencephalogram Signatures of Loss and Recovery of Consciousness from Propofol
- The Ageing Brain: Age-dependent Changes in the Electroencephalogram During Propofol and Sevoflurane General Anesthesia
- Intraoperative Burst Suppression is Associated with Postoperative Delirium Following Cardiac Surgery: A Prospective, Observational Study
- Intraopertive Electroencephalogram Suppression Predicts Postoperative Delirium
- General Anesthesia, Sleep, and Coma
- Ageing Delays Emergence from General Anaesthesia in Rats by Increasing Anaesthetic Sensitivity in the Brain
- Burst-Suppression Ratio Underestimates Absolute Duration of Electroencephalogram Suppression Compared with Visual Analysis of Intraoperative Electroencephalogram
- Effects of Sevoflurane and Propofol on Frontal Electroencephalogram Power and Coherence